mutation frequency meaning in English
(突变频率)：在种群中某个突变被发现的频率。
突变率
突变频率
Examples
- Effect of combined treatment of caffeine benzamide and 137cs - ray on mutation frequency in soybean
射线复合处理提高大豆突变频率的研究 - An expression vector with fragment 9 in antisense orientation was constructed to block the expression of the relevant gene ( fragment 9 related gene , fnr gene ) in vero cells . interestingly , we found that the nontargeted mutation frequency induced by mnng was increased significantly , implicating that the product of the blocked gene may be involved in the inhibition of nontargeted mutation
利用反义核酸技术构建含反向插入9号片段的真核细胞表达重组体并转染细胞，以获得反义rna阻断vero细胞中相应基因的表达，发现mn ’ ng诱发的非定标性突变频率显著增高，提示被阻断的相关基因的表达产物可能参与抑制非定标性突变的发生。 - In our laboratory , a unique mutation detection system using a shuttle vector plasmid has been established to demonstrate that a low concentration of mnng ( 0 . 2 m ) can induce nontargeted mutation in mammalian cells : the mammalian cells were exposed to 0 . 2m mnng for 2 . 5h , then a shuttle plasmid pz189 carrying supf trna gene was transfected into cells after 24h culture . we found a 5 - fold higher mutation frequency of the plasmid replicated in pretreated cells than the spontaneous mutation frequency of the plasmid replicated in control cells . this kind of mutation did not occur immediately after mnng exposure
我们实验室曾用一特殊的突变检测系统，直接证明dna损伤剂可在哺乳动物细胞诱发非定标性突变：首先用低浓度( 0 . 2 m )的短寿烷化剂mnng (半寿期为1 . 1hr )处理细胞2 . 5h后，继续培养24h ，将重组有用作突变检测的靶基因supftrna基因的穿梭质粒pz189转入细胞复制，发现在未受致癌物直接攻击的穿梭质粒中有较自发突变率高5倍以上的靶基因突变。